Search results for "β2 agonists"

showing 3 items of 3 documents

Use of ICS/LABA (extra-fine and non-extra-fine) in elderly asthmatics.

2016

Age represents an exclusion criterion in randomized clinical trials designed to test the efficacy and safety of inhaled drugs in asthma. As a consequence, data on efficacy and safety of inhaled corticosteroid (ICS) and long-acting β2 agonist (LABA) combinations in elderly asthmatics are scanty. Older age is associated with an increased proportion of comorbid conditions; in addition, all organ functions undergo a process of senescence, thus reducing their ability to metabolize the agents. Overall, these age-associated conditions may variably, and often unpredictably, affect the metabolism and excretion of respiratory drugs. However, pharmacological treatment of asthma does not follow specifi…

Druglong-acting β2 agonistmedicine.medical_specialtyasthma treatmentmedia_common.quotation_subjectPopulationReviewSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialPharmacokineticsInhaled corticosteroidlawmedicinePharmacology (medical)General Pharmacology Toxicology and PharmaceuticseducationAdverse effectIntensive care medicineAsthmamedia_commoneducation.field_of_studyChemical Health and SafetyInhalationbusiness.industryaginglung functionGeneral Medicinemedicine.diseasecomorbidity030228 respiratory systemAnesthesiaPharmacodynamicslong-acting β2 agonistsinhaled corticosteroidsbusinessSafety ResearchTherapeutics and clinical risk management
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New fixed bronchodilator combinations of a long-acting β2-agonist and a long-acting anticholinergic

2012

Long actingbusiness.industrymedicine.drug_classβ2 agonistsBronchodilatorAnticholinergicMedicinePharmacologybusinessAddressing Unmet Medical Needs in COPD Management
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Analysis of β2-agonists in cattle hair samples using a rapid UHPLC–ESI–MS/MS method

2016

A simple and efficient method was developed for simultaneous analysis of five illegal residual β2-agonists in cattle hair. β2-Agonists were quantified by ultra high performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry operating in positive multiple-reaction monitoring mode. The method was validated as quantitative confirmatory method according to the EU Decision 2002/657/EC: instrumental linearity, specificity, precision, recovery, decision limit (CCα) and detection capability (CCβ) were evaluated. The recovery were greater than 90% and the method appeared suitable for the control of these β2-agonists in cattle hair samples with LOQ values between …

UHPLC –ESI–MS/MSβ2-agonist0301 basic medicineElectrospray030109 nutrition & dieteticsChromatographycattle hair; Commission Decision 2002/657/EC; UHPLC–ESI–MS/MS; β2-agonists; Plant Science; Biochemistry; Analytical Chemistry; Organic ChemistryChemistryβ2 agonistsElectrospray ionization010401 analytical chemistryOrganic ChemistryPlant ScienceContaminationTandem mass spectrometry01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry03 medical and health sciencesCommission Decision 2002/657/ECcattle hairAdrenergic beta-AgonistsUltra high performanceDecision limitNatural Product Research
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